TRPC6 Inhibitor
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TRPC5-IN-7
0 ImagesCat. No.: HY-189736TRPC5-IN-7 is an orally active TRPC5 inhibitor (hTRPC5: IC50 = 0.77 μM). TRPC5-IN-7 inhibits the TRPC5 cation channel and TRPC5-mediated calcium influx by binding to the VSLD allosteric pocket, with selectivity for TRPC5 over TRPC3 and TRPC6. TRPC5-IN-7 exerts anxiolytic effects in mice and can be used for anxiety research.
